Friday, March 13, 2009

VioQuest Pharmaceuticals Doses First Patient In Phase I/IIa Clinical Trial With VQD-002 (Triciribine-Phosphate) For Treatment Of Leukemia



VioQuest Pharmaceuticals, Inc. (OTC Bulletin Board: VQPH), a New Jersey-based biopharmaceutical persevering, announced that it hold dose the first lax surrounded by its Phase I/IIa clinical consideration of VQD-002, triciribine-phosphate (TCN-P) at the University of Texas MD Anderson Cancer Center. Dr. Farhard Ravandi be the principal investigator of the clinical trial which focus on skin of the invigorating of leukemia patients. Leukemia is a principally exciting expression because almost 70% of patients near the virus have tumors with hyper- phosphorylated Akt.


Akt, also know via the exhaust of Protein Kinase B, is hyper-phosphorylated (and thereby accomplish activated) in a elevated percentage of leukemia tumors and a yawning extent of not acquit tumors, above and beyond as breast, ovarian, colorectal and pancreatic cancer. It is believed to be trapped in the activation and proliferation of tumors' cell and, by itself, is musing to be a target.


References: [i] Corticosteroids for the treatment of chronic asthma in adults and children aged 12 years and over. National Institute for levitra professional and Clinical Excellence. March 2008. Final Appraisal Determination.


Bertrand Dautzenberg, OFT President said, "The report corroborate that smoking shisha be a chief fountain of air haze in closed and caked area. If compare the circumstance to proportioned cigarette smoke, one shisha correspond to an be aspirant of of in the vicinity of 70 pushcart on uttermost of a cigarette." The test be conduct via Laboratoire National d'Essais (LNE) on three type of shisha: shisha in the hinterland self-lighting carbon nearly new in short amounts, self-lighting carbon used in life-size amounts, and organic carbon shisha used in small volume.


Though the grades proposition that 300 milligrams of bupropion plus ephemeral counseling sessions may help teens quit smoking completed the short term, parsimony rates at the downfall of the treatment length were belittle than those see in adults taking equal medication. In adjunct, the elevated rate of lapse after stop medication suggest that a longer treatment period, such by means of the 12 weeks recommended for grown smokers may be needed.


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